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  1. CREST-2: Medical study to prevent stroke caused by plaque buildup in ...

    What is the purpose of CREST-2? CREST-2 is designed to compare three different methods of stroke prevention to find the safest and most effective treatment.

  2. CREST-2: Stents But Not Endarterectomy Reduced Stroke Risk For ...

    Dec 2, 2025 · Among patients with asymptomatic carotid artery stenosis (CAS), the addition of stenting to medical therapy led to a significantly lower risk of stroke compared with medical therapy alone, …

  3. Revascularization for Asymptomatic Carotid Stenosis — The CREST-2

    Dec 3, 2025 · Randomized trials from decades ago showed that patients with asymptomatic carotid stenosis could benefit from endarterectomy in the long run if they would accept early risks for …

  4. CREST-2: percutaneous carotid stenting plus intensive medical therapy ...

    Dec 4, 2025 · In CREST-2, percutaneous carotid artery stenting combined with intensive medical therapy significantly reduced the 4-year risk of stroke or death compared with medical therapy alone, …

  5. Long-Awaited CREST-2 Results Bolster Stents for Asymptomatic …

    Nov 21, 2025 · In addition to providing support to stenting, the CREST-2 results likely will boost transcarotid artery revascularization (TCAR), a procedure that weds both surgical and percutaneous …

  6. Study Details | NCT02089217 - ClinicalTrials.gov

    Oct 1, 2025 · Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical …

  7. CREST-2: Landmark trial finds benefit from carotid stenting

    Nov 22, 2025 · The National Institutes of Health (NIH)-funded CREST-2 study has found that, for people with high-grade asymptomatic carotid artery stenosis who have not experienced recent stroke …

  8. CREST‐2 Commitment to Rigorous Assessment of Carotid Stenting for ...

    Apr 5, 2024 · CREST‐2 (Carotid Revascularization, Endarterectomy Versus Stent Trial)‐2 is a set of 2 separate 2‐arm randomized trials where one trial compares intensive medical management with and …

  9. Carotid Revascularization and Medical Management for Asymptomatic ...

    Jul 25, 2022 · Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical …

  10. CREST-2 Boosts Modern Medical Therapy for the Initial… | Clinician.com

    The CREST-2 results have immediate implications for management of asymptomatic carotid stenosis, affirming that intensive medical therapy alone suffices for most patients, with revascularization …