Week 4 of college football brings more uniform heat with deep meanings. After losing to the Missouri Tigers in Week 3, who knocked them out of the AP Top-25 rankings, the Boston College Eagles are looking for vengeance Saturday when they take on the Michigan State Spartans.

Week 4 of college football brings key matchups such as Illinois at Nebraska and USC at Michigan. Get expert betting insights and odds for top games.

Here are the five biggest "must-watch" games on the docket for this weekend. While this game may not be the most exciting, Arch Manning is scheduled to make his first start for the Longhorns. That alone makes this game a must-watch on the schedule to see how he can perform.

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