A new study published in Nature offers the most detailed map to date of how individual cell types in the brain change with age. Scientists analyzed over 1.2 million brain cells from young and aged ...

Researchers from Charité - Universitätsmedizin Berlin and the Max Delbrück Center have identified the precise mechanism by ...

CD2AP and synaptic integrity: A double-edged sword Synapse loss is a strong predictor of cognitive decline in AD, and CD2AP is crucial for maintaining synaptic structure and function. However ...

In the present study, via the condition knockout strategy to generate mosaic microglia population in adult zebrafish and mice, we revealed that the turnover and maintenance of microglia is ...

Microglia, the brain’s immune cells ... for Multidisciplinary Sciences in Göttingen also showed how myelin structure and nerve fiber density changed depending on whether the IL-12 signaling ...

Microglia, the brain's immune cells ... for Multidisciplinary Sciences in Göttingen also showed how myelin structure and nerve fiber density changed depending on whether the IL-12 signaling ...

Microglia, the brain's immune cells ... for Multidisciplinary Sciences in Göttingen also showed how myelin structure and nerve fiber density changed depending on whether the IL-12 signaling ...

More information: Churmy Y. Fan et al, Divergent sex-specific pannexin-1 mechanisms in microglia and T cells underlie neuropathic pain, Neuron (2025). DOI: 10.1016/j.neuron.2025.01.005 ...

Plaques all but vanish in response to some Aβ immunotherapies. Scientists suspect microglia orchestrate the mop-up, but don’t know how, exactly. Now, David Gate of Northwestern University in Chicago ...

ABSTRACT: Microglia, the central nervous system’s resident immune cells, play a pivotal role in brain development and function, particularly in pediatric neurological disorders. This review explores ...