The researchers also showed that the circles can contain not just cancer-driving oncogenes and genes that modulate the immune response, but also that others can contain only DNA sequences called ...

Tiny circles called ecDNA are critical in cancer development and drug resistance. An international team publishes landmark studies detailing new findings and potential therapies.

Can small circles of DNA, once dismissed as irrelevant, actually be major contributors to cancer development? Three new research studies ... | Genetics And Genomics ...

DNA catapults into spotlight. A trio of research papers from Stanford Medicine researchers and their international collaborators transforms scientists’ understanding of how small DNA circles — until ...

Transcription activation of genes by estrogens is driven by enhancers, which are often located within the same Topologically Associating Domain (TAD) as non-targeted promoters. We investigated how ...

A breakthrough tool called Helicase-Assisted Continuous Editing (HACE) allows scientists to create precise genetic mutations ...