The Astros opened the series with a 4-3 win over Tampa Bay. The Rays battled back from an early 3-0 deficit only to lose the game on a Jake Meyers’ home run in the seventh inning. Josh Hader closed the game in the ninth for his 12th save of the season.

Get Tampa Bay vs Houston baseball betting preview, spread and over/under insights for their matchup on May 20.

Houston Astros starting pitcher Hayden Wesneski is set to undergo Tommy John surgery that will sideline him rest of the season and put his 2026 campaign in jeopardy, as well. The Astros have been dealing with pitching injuries like no other team.