In an autologous stem cell transplant, you are donating and receiving your own stem cells. In an allogeneic stem cell ...

PBFT02 continued to demonstrate robust, durable elevation in CSF PGRN levels and improvement in plasma NfL, a disease progression biomarker, compared to natural history Dose 2, 50% lower than Dose 1 ...

Antiretroviral therapy (ART) initiated in the acute phase of HIV infection (AHI) results in a smaller viral reservoir. However, the impact of early HIV-specific T-cell responses on long-term reservoir ...

The IsKia trial reveals that isatuximab enhances MRD negativity in newly diagnosed multiple myeloma, especially in high-risk ...

Studies in both experimental animals and humans uniformly indicate that a large gradient exists between plasma and CSF insulin concentrations in healthy individuals, with plasma concentrations ...

Similarly, preclinical models have shown that plasma and CSF NfL levels can indicate axonal health and disease progression in models of neurodegenerative and neuroinflammatory diseases.

These data continue to show that CAR T-cell therapy—in this case, targeting B-cell maturation antigen—clearly is effective in myeloma. It improves depth of remission, duration of remission, and ORR ...

In this study, we employed MR to (1) systematically screen 608 brain, 214 CSF, and 612 plasma proteins to identify novel targets for ADHD; (2) explore whether identified risk proteins share genetic ...

Plasma cells in the MS CSF up-regulate diverse pathways implicated in pro-inflammatory signalling and antibody synthesis, including TNFα and mTORC1 signalling, compared with their peripheral ...

Potential donors often get granulocyte colony stimulating factor (G-CSF) to help collect the cells from the marrow. But G-CSF could cause a reaction if you have MS.

BioLineRx Announces FDA Approval of APHEXDA™ (motixafortide) in Combination with Filgrastim (G-CSF) to Mobilize Hematopoietic Stem Cells for Collection and Subsequent Autologous Transplantation in ...

08 Sep 2023 In the blood, lipoproteins ferry cholesterol and other lipids to cells throughout the body. In the cerebrospinal fluid, they may do the same, but because they are 200-fold more dilute ...