Antiretroviral therapy (ART) initiated in the acute phase of HIV infection (AHI) results in a smaller viral reservoir. However, the impact of early HIV-specific T-cell responses on long-term reservoir ...

PBFT02 continued to demonstrate robust, durable elevation in CSF PGRN levels and improvement in plasma NfL, a disease progression biomarker, compared to natural history Dose 2, 50% lower than Dose 1 ...

Analogous findings are reported for the leptin plasma/CSF gradient, ... In aortic endothelial cells, the IR is associated with caveolae, and the knockdown of caveolin-1 ...

BioArctic AB (publ) (NASDAQ Stockholm: BIOA B) announced today that the interim safety review of the clinical Phase 2a study EXIST showed exidavnemab to be safe and well-tolerated, whereby the second ...

The CAR T cell therapy, called NXC-201, targets a protein called BCMA, which is expressed on the surface of amyloid plasma cells and drives cancer growth. In the first 10 patients to receive the ...

Cells signaled an antitumor effect, ... (CSF) -- had a response that started in 1 month and lasted 4 months, Stephen Bagley, MD, of the University of Pennsylvania in Philadelphia, ...

The IsKia trial reveals that isatuximab enhances MRD negativity in newly diagnosed multiple myeloma, especially in high-risk ...

This article explores the complex roles of cytokine networks in the development and progression of autoimmune diseases.

CHICAGO -- Intracerebroventricular (ICV) delivery of bivalent CAR T-cells targeting EGFR and IL13Rα2 was feasible and appeared safe in patients with recurrent glioblastoma (GBM) in a phase I ...

Distribution of plasma AD biomarkers by diagnosis and CSF p-tau181/Aβ42. (CREDIT: Alzheimer's and Dementia) Of the patients tested, blood biomarkers positively identified Alzheimer's in 267 ...