A research team led by The University of Osaka finds that elevated levels of certain immune cells in patients with systemic ...

Treating rare diseases can be complicated at the best of times, and it gets even more complicated when different patients ...

RNA-seq and spatial transcriptomics showed immune cell subsets that drive kidney and lung complications in systemic sclerosis ...

In cells expressing CD14 (as seen with ‘professional’ antigen-presenting cells), CD14 was a co-receptor of the putative HSP70 receptor (Table 1 and Fig. 4).

"The results were intriguing," explains Masayuki Nishide, senior author. "We identified a specific subset of immune cells, the EGR1 -expressing subpopulation of CD14+ monocytes, that were clearly ...

Whether antiretroviral therapy (ART) is always completely suppressive, or HIV might continue to replicate at low levels despite ART in some people with HIV (PWH), is still debated. Here, we ...

Objective To determine the prevalence of upregulation of interferon (IFN) type I inducible genes, the so called ‘IFN type I signature’, in CD14 monocytes in 69 patients with primary Sjögren's syndrome ...

Higher expression of interferon-driven genes is linked to better response to methotrexate in patients with juvenile ...

"While most organs are thought to be shaped by static, brick-like cells, our study highlights the powerful role of dynamic, migrating cells—and how they work together to sculpt living tissue ...