Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC). This ...

Cancer is a complex group of diseases and is often caused by a combination of genetic, environmental, and lifestyle factors. And when we talk about lifestyle factors, our dietary choices play a ...

More information: Abhisek Dwivedy et al, Engineering Novel DNA Nanoarchitectures for Targeted Drug Delivery and Aptamer Mediated Apoptosis in Cancer Therapeutics, Advanced Functional Materials (2025).

Researchers at the Max Planck Institute of Biochemistry investigate the structure of these proteins and how they function – from individual molecules through to complex organisms. They make use of the ...

Researchers have developed a machine-learning workflow to optimize the output force of photo-actuated organic crystals. Using LASSO regression to identify key molecular substructures and Bayesian ...

And while programmed cell death (apoptosis) is a critical mechanism for deleting faulty and old cells in order for the body to regenerate new, more productive cells, HFSCs even at their most ...

National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230026, China Department of Pathology, The First Affiliated Hospital of USTC, Division of Life Sciences ...

This study aimed to elucidate the molecular mechanism of TNIP1 regulation in the proliferation and apoptosis of breast cancer cells. A colony formation assay was conducted on MCF-7 and T47D cells ...

Beat-Va M remodeling was unaffected, but this blockade prevented apoptosis in Beat-Va L cells. Next, they explored remodeling in the Beat-Va M neurons. “The surprising thing is that it is ...

Upon activation, NLRP3 binds to apoptosis-associated speck-like protein containing a caspase activation and recruitment domain (ASC). ASC then polymerizes to form a large aggregate known as an ASC ...