A red flag warning has been issued for the Inland Empire and some cities in the Coachella Valley as strong gusty winds and low humidity are expected early next week. The warning is in effect from 10 a.

The National Weather Service issued a Red Flag Warning starting Monday for San Diego County's inland valleys and mountains.

Nearly 100,000 San Diegans could loose power during the next round of power shutoffs after the National Weather Service issued another Red Flag Warning for the region for Monday and Tuesday as Santa Ana winds return.

This weekend's cool temperatures and higher humidity are expected to give way to more Santa Anas and a new red flag warning Monday.

As firefighters struggle to gain control of massive and deadly wildfires that are raging across parts of the Los Angeles area, the region is once again bracing for the potential of new fires and for current ones to intensify as a new storm system heads for the state.

The new alert is an unprecedented fifth issuance of a “particularly dangerous situation” enhancement to a red flag warning in a single season by the weather service’s Oxnard office, which covers Los Angeles, Ventura, Santa Barbara and San Luis Obispo counties.

Californians in the greater Los Angeles area have been on edge due to high winds and dry conditions. The Palisades and Eaton fires have killed at least 25 and destroyed thousands of homes.

Gusts of up to 70 mph are possible along the coast and valleys, and in the mountains, up to 100 mph, the National Weather Service said. Parts of L.A. County, and most of Ventura County, are at highest risk.

A “particularly dangerous situation” red flag warning for fire weather was set to kick in at noon Monday and last until 10 a.m. Tuesday.

Los Angeles County officials urged the public to prepare Monday as Southern California braced for the return of dangerous Santa Ana winds and extreme fire conditions. The National Weather Service

Jan. 8, 1:25 p.m. PST The Palisades Fire in Los Angeles’ Pacific Palisades—an affluent coastal neighborhood—exploded to 15,832 acres, according to Cal Fire, making it the largest fire of the four burning in Los Angeles County as of Wednesday afternoon.