A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.
And finally, you know, if we're targeting that osteoclast, there may be other ways of speaking to the osteoclast, through other kinds of signaling, and there are drugs like that, that are in the ...
While several scientific reports have revealed the distinct regulatory mechanisms of osteoclast and osteoblast differentiation, little is known about the common factors that influence the ...
A recent study that is yet to be published provided insights into the process of osteoclast differentiation and revealed potential therapeutic targets which can be pursued to develop treatments ...
A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.
A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming ...
TNFRSF11A encodes the receptor activator of NFκB (RANK), which is critical for normal osteoclast formation; genetic variants in this gene result in familial expansile osteolysis, a Paget-disease ...
A disruption in the interplay between the bone-building osteoblast cells and the bone-degrading osteoclast cells can lead to osteoporosis. Most existing therapies reduce osteoclast activity ...