Review of the emerging understanding of trained immunity in the skin and how infection-driven cellular processes induce long-lasting immune adaptation and modulate skin barrier integrity.
In experiments with mouse models of breast, pancreatic, and muscle cancers, researchers at Johns Hopkins All Children's Hospital report new evidence that a novel means of boosting the natural immune ...
Researchers wanted to understand how steroids selectively affect human macrophages, which are a key cellular player in the ...
T-cell exhaustion and pre-existing T-cell immunity in circulation as predictive biomarkers for immunotherapy in NSCLC patients. Monitoring PD-L1 expression in cancer-associated macrophage-like cells ...
Myc dysregulation in activated macrophages impairs antioxidant defenses, locking them in a vicious cycle that amplifies type I interferon signaling, driving hyperinflammation and immunosuppression.
Approximately 9.5 million people globally live with type 1 diabetes, a chronic autoimmune disease where T cells from the body ...
Esophageal squamous cell carcinoma (ESCC) is a deadly cancer with particularly high prevalence in East Asia. While immunotherapy has emerged as a promising treatment, many patients fail to ...
Researchers generated the most comprehensive single-nucleus transcriptomic atlas of pig intestines to date, covering wild boars and domestic pigs across four key postnatal developmental stages. The ...
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