From there, the Division Series will begin on Saturday, Oct. 4, with the League Championship Series getting underway no earlier than Sunday, Oct. 12. The 2025 World Series, meanwhile, will kick off on Friday,

For one, all four Wild Card series are set to begin on Sept. 30, which lands on a Tuesday. That's two days after the Tigers are set to play their final game of the regular season, a road game against the pennant-chasing Boston Red Sox.

With the Cardinals retooling and the Pirates being, well, the Pirates, there isn't much that would seem to stand in the way of Milwaukee and Chicago doing battle atop this division yet again. The head-to-head matchups are going to be crucial, and none will be bigger than these four.