B-cell acute lymphoblastic leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most ...

Explore a high-throughput picodroplet-based method for CAR-T cell functional validation that enables rapid, single-cell ...

Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing ...

Axi-cel, tisa-cel, and brexu-cel were found comparable to other cellular therapy experiences for patients with B-cell ...

Decoy increases effectiveness of treatment in B-cell acute lymphoblastic leukaemia B-cell Acute Lymphoblastic Leukaemia ...

These cells can't fight infections well ... Different types of targeted therapy focus on other interactions between cancer cells. B-cell lymphoma is a type of cancer that affects white blood ...

By contrast, naive B cells produce IL-10 when stimulated in a 'bystander' activation context through non-cognate interaction with an activated T cell (CD40 signalling only, independent of either ...

More information: Jonas Nørskov Søndergaard et al, Single cell suppression profiling of human regulatory T cells, Nature Communications (2025). DOI: 10.1038/s41467-024-55746-1 Provided by Osaka ...

Cullinan Therapeutics rebranded from oncology to immunology+oncology, focusing on CD19 TCEs for autoimmune diseases. Check ...

Many other signals (both secreted chemicals and cell-cell surface interactions ... and Nicholson, L. B. (2010) TNFR1 signalling is a critical checkpoint for developing macrophages that control T-cell ...