Scientists use cell death, whether by apoptosis or necrosis, to evaluate the toxicity or effectiveness of substances of interest, including potential therapeutic agents. For example, researchers will ...

The released miR-503-3p suppresses BAK, a protein that promotes apoptosis, thereby preventing radiation-induced cell death (apoptosis). As a result, radiation-sensitive cells acquire radioresistant.

Journal of Cellular Biochemistry 104(1): 339-356 ... Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo.

This study aimed to elucidate the molecular mechanism of TNIP1 regulation in the proliferation and apoptosis of breast cancer cells. A colony formation assay was conducted on MCF-7 and T47D cells ...