A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a ...

The H5N1 avian influenza virus is mutating to evade immune defenses in mammals following prior infection or vaccination.

CoV-2 nucleocapsid antibodies to detect exposure to SARS-CoV-2: results from a prospective cohort study on COVID-19 ...

Successful high-affinity B cells can proliferate under special conditions that reduce the risk of mutation. Capturing this ...

and affinity maturation in one platform, meaning that we can go from antigen to primary hit antibodies in seven days,” said Lin. “Our technology uses the power of cells to create unique gene ...

the two produced a fusion protein with all of the antigen binding properties of a full antibody, which they called single chain Fv (scFv). This scFv was expressed by the bacteriophage and could be ...

Antibody sequences Remaining antigens Top three humanized antibodies, 0.2~0.5 mg per strain (at least one humanized ab has an equivalent affinity with parental ab) CoA H and L chains in separate ...

Immunoglobulins sample vast swathes of primary sequence and conformational space to generate and select B cell clones with exquisite selectivity and affinity for specific antigens. This ...

Leveragen Inc., a Boston-based biotechnology company specializing in next-generation genetic models for antibody discovery, ...

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate ... mutations that enhance their affinity for an antigen. As a consequence, high-affinity B cell ...