Figure 1: Chemical structure of amides and the conventional chemical method for amide bond synthesis. Figure 2: Representation of protein and peptide synthesis by biochemical and chemical methods. The ...

A pair of copper catalysts can create chiral amides in a new, light-driven process, offering a useful alternative to the standard method for making these staples of medicinal chemistry (Nature 2021, ...

While I really loved the elegant chemistry highlighted in Bethany Halford's article titled "Amide with a Twist," twisted amides are not that unusual and are indeed naturally occurring in some of ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amide Technologies, a leading biotech company specializing in the synthesis of complex peptides, announced today the appointment of Dr. Brad Pentelute as its new CEO ...

The structure fluctuations of the peptide bond interacting with solvent are examined through the coupling and correlations of the frequency distributions of amide I and amide II transitions. The ...

In protein formulations, native-state unfolding and aggregation is of critical importance to both patients and manufacturers. Product quality and safety concerns need an understanding of aggregation ...

Standard methods for protein quantitation rely on colorimetric assays like those involving protein-copper chelation (BCA and Lowry assays) and dye-binding based detection (Bradford and 660 Assay) or ...

There have been significant developments in recent years regarding thermal treatments, which are beginning to replace traditional techniques in the preservation of highly perishable products. This has ...